I-Endemic isho uhlobo lwesitshalo noma lwesilwane oluhlukile futhi olukhethekile endaweni ethile noma endaweni ethile.. Izinhlobo zezilwane ezihlala kuzo zitholakala kuphela endaweni ethile futhi azitholakali kwenye indawo emhlabeni.
Lokhu kungenzeka ngezizathu eziningana, kuhlanganise geological, isimo sezulu, kanye nezici zemvelo ezidala indawo eyingqayizivele efanele ukuphila nokwanda kohlobo oluthile. Ukuhlukaniswa kwezinye izifunda nakho kungaholela ekuthuthukisweni kwezimpawu zofuzo eziyingqayizivele kanye nokujwayela kwezinhlobo zezilwane ezivumela ukuthi zichume endaweni ethile..
Izinhlobo ezihlala ezindaweni ezihlala kuzo zivame ukubhekwa njengenani eliphezulu lokongiwa, njengoba zimelela ingxenye eyingqayizivele yemvelo ehlukahlukene yesifunda kanye ne-ecosystem. Bangase basongelwa ukulahlekelwa indawo yokuhlala, ukushintsha kwesimo sezulu, noma ezinye izici zemvelo, okungaholela ekwehleni kwenani labantu noma ngisho nokushabalala.
Izibonelo zezinhlobo ezihlala zikhona zihlanganisa ufudu olukhulu lwe-Galapagos, etholakala kuphela eziQhingini zaseGalapagos ngasogwini lwase-Ecuador, kanye ne-mountain pygmy possum, etholakala kuphela ezindaweni ezisezintabeni eziseningizimu-mpumalanga ye-Australia.